ALBUTEROL (PROVENTIL, VENTOLIN)

Class

Sympathomimetic (B₂Selective)

Pharmacology and Actions

1. Has selective beta-adrenergic stimulating properties resulting in potent bronchodilation.
2. Rapid onset of action (under 5 minutes), and duration of action between 2 - 6 hours.

Indications

1. For relief of bronchospasm in patients with obstructive airway disease (asthma, emphysema, COPD) or allergic reactions.

Contraindications

1. Symptomatic tachycardia
2. Known hypersensitivity to drug

Precautions

1. Albuterol sulfate has sympathomimetic effects. Use with caution in patients with known coronary disease. Monitor pulse, blood pressure, and cardiac monitor, in CAD patients.
2. When inhaled, albuterol sulfate can result in paradoxical bronchospasm, which can be life threatening. If this occurs, the preparation should be discontinued immediately.

Administration

1. For nebulizer use only
   1. For adults and children: place 2.5 mg/3mL albuterol into an oxygen­-powered nebulizer and run at 6-8 LPM. Deliver as much of the mist as possible by nebulizer over 5-15 minutes.
   2. Endotracheally intubated patients may be given albuterol sulfate by attaching the nebulizer in-line.
   3. Patients placed on CPAP may be given albuterol sulfate by attaching the nebulizer in-line.

Side Effects and Special Notes

1. Monitor blood pressure and heart rate closely and contact medical control if any concerns arise.
2. Medications such as MAO inhibitors and tricyclics may potentiate tachycardia and hypertension.